6-(3-Chlorophenyl)picolinic acid → 6-(3-chlorophenyl)-N-[2-cyclopropyl-1-(1,3-thiazol-2-yl)ethyl]pyridine-2-carboxamide
Reaction equation
[CH:17]1([CH2:20][CH:21]([c:22]2[s:23][cH:24][cH:25][n:26]2)[NH:27][C:28]([c:29]2[cH:30][cH:31][c:32]([CH:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[c:39]([O:40][CH2:41][CH:42]3[CH2:43][CH2:44]3)[n:45]2)=[O:46])[CH2:18][CH2:19]1.[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[cH:9][cH:10][cH:11][c:12]([C:14](=[O:15])[OH:16])[n:13]2)[cH:5][cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[cH:9][cH:10][cH:11][c:12]([C:14](=[O:16])[NH:27][CH:21]([CH2:20][CH:17]3[CH2:18][CH2:19]3)[c:22]3[s:23][cH:24][cH:25][n:26]3)[n:13]2)[cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-49b6f2d3ae97417092fcc396370fd911
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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