1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-2-methylene-1-butanone → 1-[2-Chloro-4-(3-diethylaminopropoxy)phenyl]-2-methylene-1-butanone

HRID 66606Notes

Reaction equation

HRID 66606 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10]N(CC)CC)[CH:5]=[CH:4][C:3]=1[C:16](=[O:21])[C:17](=[CH2:20])[CH2:18][CH3:19].ClC1C=C(OC[CH2:31][CH2:32][N:33]([CH2:36]C)[CH2:34][CH3:35])C=CC=1C(=O)CCC>>[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10][CH2:36][N:33]([CH2:34][CH3:35])[CH2:32][CH3:31])[CH:5]=[CH:4][C:3]=1[C:16](=[O:21])[C:17](=[CH2:20])[CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 130523721-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-2-methylene-1-butanoneHCID 204971651-[2-Chloro-4-(3-diethylaminopropoxy)phenyl]-1-butanone

Product 1

HCID 130523761-[2-Chloro-4-(3-diethylaminopropoxy)phenyl]-2-methylene-1-butanone

Procedure

This compound is prepared by essentially the same method as described in Example 1 Step B except that the 1-[2-chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone of Example 1 Step B is replaced by an equimolecular quantity of 1-[2-chloro-4-(3-diethylaminopropoxy)phenyl]-1-butanone. The product is obtained as a yellow oil upon distillation in vacuo (0.4 mm.).

Workup

  1. customThis compound is prepared by essentially the same method
  2. customThe product is obtained as a yellow oil upon distillation in vacuo (0.4 mm.)

Sources & evidence

ORD record
ord-c13b36dfc6464f1398a2611292d71bef
Source dataset
uspto-grants-1982_08
Patent number
US04342782

Reaction notes

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