HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Chloroethyl)pyrrolidine hydrochloride → 1-{2-Chloro-4-[2-(N-pyrrolidinyl)ethoxy]-phenyl}-1-butanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Chloroethyl)pyrrolidine hydrochloride | HCID 81668 | — |
| Reactant | 1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone | HCID 13052371 | — |
| Product | 1-{2-Chloro-4-[2-(N-pyrrolidinyl)ethoxy]-phenyl}-1-butanone | HCID 20497166 | — |
Reaction Steps
This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1 Step A is replaced by an equimolecular quantity of N-(2-chloroethyl)pyrrolidine hydrochloride. The product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04342782 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-3b2fef9249ba4fb9b8c9f123edf9d8cb |
| Source note | uspto-grants-1982_08 |