Piperidine, 1-(2-chloroethyl)-, hydrochloride → 1-[2-Chloro-4-(2-piperidinoethoxy)phenyl]-1-butanone

Participants

Reaction Steps

This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1 Step A is replaced by an equimolecular quantity of N-(2-chloroethyl)piperidine hydrochloride. The product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.).

Provenance & Evidence