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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66612Generated: October 27, 2026

1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-2-methylene-1-butanone → 1-[2-Chloro-4-(2-piperidinoethoxy)phenyl]-2-methylene-1-butanone

https://huagongshe.com/reaction/66612

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-2-methylene-1-butanoneHCID 13052372—
Reactant1-[2-Chloro-4-(2-piperidinoethoxy)phenyl]-1-butanoneHCID 20497174—
Product1-[2-Chloro-4-(2-piperidinoethoxy)phenyl]-2-methylene-1-butanoneHCID 13052374—

Reaction Steps

This compound is prepared by essentially the same procedure as described in Example 1 Step B except that the 1-[2-chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone of Example 1 Step B is replaced by an equimolecular quantity of 1-[2-chloro-4-(2-piperidinoethoxy)phenyl]-1-butanone. The product is obtained as a yellow oil upon distillation in vacuo (0.3 mm.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04342782
Source datasetuspto-grants-1982_08
ORD IDord-87b9c2886e184b4c99cd8c92a13d0daf
Source noteuspto-grants-1982_08