Isopropyl chloroformate → 1-(Isopropoxycarbonyl)piperidin-4-yl 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylate
Reaction equation
[Cl:1][C:2](=[O:3])[O:4][CH:5]([CH3:6])[CH3:7].[NH2:8][c:9]1[n:10][c:11]([N:34]2[CH2:35][CH2:36][N:37]([CH3:40])[CH2:38][CH2:39]2)[cH:12][c:13](-[c:15]2[cH:16][cH:17][c:18]3[c:23]([cH:24]2)[CH2:22][N:21]([C:25](=[O:26])[O:27][CH:28]2[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]2)[CH2:20][CH2:19]3)[n:14]1>>[C:2](=[O:3])([O:4][CH:5]([CH3:6])[CH3:7])[N:31]1[CH2:30][CH2:29][CH:28]([O:27][C:25]([N:21]2[CH2:20][CH2:19][c:18]3[cH:17][cH:16][c:15](-[c:13]4[cH:12][c:11]([N:34]5[CH2:35][CH2:36][N:37]([CH3:40])[CH2:38][CH2:39]5)[n:10][c:9]([NH2:8])[n:14]4)[cH:24][c:23]3[CH2:22]2)=[O:26])[CH2:33][CH2:32]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-1e8bef7e19ab4e4ba06a2c6647d6e033
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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