1'-benzyloxy-2,3-dihydro-6-fluoro-2-(2-propyl)-spiro-(4H-1-benzopyran-4,3'-pyrrolidine)-2'one → 1'-hydroxy-2,3-dihydro-6-fluoro-2-(2-propyl)-spiro-(4H-1-benzopyran-4,3'-pyrrolidine)-2'-one
Reaction equation
[CH2:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[O:23][N:24]1[C:25](=[O:42])[C:26]2([CH2:27][CH:28]([CH:37]([CH3:38])[CH3:39])[O:29][c:30]3[c:31]2[cH:32][c:33]([F:36])[cH:34][cH:35]3)[CH2:40][CH2:41]1.[F:1][c:2]1[cH:3][cH:4][c:5]2[c:14]([cH:15]1)[C:12](=[O:13])[CH2:11][CH:7]([CH2:8][CH2:9][CH3:10])[O:6]2.[F:43][c:44]1[cH:45][cH:46][c:47]2[c:61]([cH:62]1)[C:59](=[O:60])[CH2:58][CH:49]([CH2:50][CH2:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1)[O:48]2>>[OH:23][N:24]1[C:25](=[O:42])[C:26]2([CH2:27][CH:28]([CH:37]([CH3:38])[CH3:39])[O:29][c:30]3[c:31]2[cH:32][c:33]([F:36])[cH:34][cH:35]3)[CH2:40][CH2:41]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-85d91297eab24f60a633a16402099dde
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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