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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 666280Generated: November 1, 2026

1,2-Dimethoxyethane → 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(4-trifluoromethyl-benzylamino)-pyrimidine-5-carbonitrile

https://huagongshe.com/reaction/666280

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
Reactant4-(Trifluoromethyl)benzylamineHCID 76804—
ReactantTrifluoromethanesulfonic acid 2-amino-5-cyano-6-(4,5-dihydro-furan-2-yl)-pyrimidin-4-yl esterHCID 86583757—
Product2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(4-trifluoromethyl-benzylamino)-pyrimidine-5-carbonitrileHCID 18507662—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-7b659eff5ae840e28bf7fd51f5b98555
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)