HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 666345Generated: October 25, 2026
1,4-Dioxane → 4-{2-[5-Chloro-4-(4-cyclopropylcarbamoyl-benzo[b]thiophen-2-yl)-pyrimidin-2-ylamino]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/666345
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate | HCID 1514258 | — |
| Reactant | 2-(2,5-Dichloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide | HCID 86625351 | — |
| Product | 4-{2-[5-Chloro-4-(4-cyclopropylcarbamoyl-benzo[b]thiophen-2-yl)-pyrimidin-2-ylamino]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester | HCID 68857840 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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| ORD ID | ord-3ac98d838e504dfb9f36c0d36e6a828d |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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