1,4-Dioxane → 2-[1-[8-Chloro-2-(1,3-thiazol-5-yl)quinolin-3-yl]ethyl]isoindole-1,3-dione
Reaction equation
[CH2:26]([Sn:27]([CH2:28][CH2:29][CH2:30][CH3:36])([c:31]1[cH:32][n:33][cH:34][s:35]1)[CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH3:43].[CH2:44]1[O:45][CH2:46][CH2:47][O:48][CH2:49]1.[Cl:1][c:2]1[n:3][c:4]2[c:5]([Cl:25])[cH:6][cH:7][cH:8][c:9]2[cH:10][c:11]1[CH:12]([CH3:13])[N:14]1[C:15](=[O:24])[c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]2[C:22]1=[O:23].[cH:50]1[cH:51][cH:52][c:53]([P:54]([Pd:55]([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([P:75]([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[P:94]([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)[cH:125][cH:126]1>>[c:2]1(-[c:31]2[cH:32][n:33][cH:34][s:35]2)[n:3][c:4]2[c:5]([Cl:25])[cH:6][cH:7][cH:8][c:9]2[cH:10][c:11]1[CH:12]([CH3:13])[N:14]1[C:15](=[O:24])[c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]2[C:22]1=[O:23]Participants
5
Sources & evidence
- ORD record
- ord-604c82f4609a47bc99c497efea8f0806
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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