Dimethyl Sulfoxide → 1-Ethoxycarbonyl-5-chloro-3-phenylisoindole-2-acetic acid ethyl ester

HRID 666823Notes

Reaction equation

HRID 666823 reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8](-[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:9]2[cH:10][c:11]([Cl:15])[cH:12][cH:13][c:14]12.[CH2:22]([CH3:23])[O:24][C:25]([CH2:26][Br:27])=[O:28].[CH3:35][S:36]([CH3:37])=[O:38].[K+:33].[K+:34]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7]([CH2:26][C:25]([O:24][CH2:22][CH3:23])=[O:28])[c:8](-[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:9]2[cH:10][c:11]([Cl:15])[cH:12][cH:13][c:14]12

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 7748Ethyl bromoacetateHCID 19660Carbonate IonHCID 54174784Ethyl 5-chloro-3-phenyl-2H-isoindole-1-carboxylate

Product 1

HCID 545612521-Ethoxycarbonyl-5-chloro-3-phenylisoindole-2-acetic acid ethyl ester

Sources & evidence

ORD record
ord-2c34ee1595624739955ad53930db0f3f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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