HRID66688

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCC1(C(C)C)Cc2cc(CC(N)=O)c(Cl)c(Cl)c2C1=O

HCID53978194

未命名化合物

结构：CC(C)C1(C)Cc2cc(CC(N)=O)c(Cl)c(Cl)c2C1=O

HCID54249387

未命名化合物

结构：CCC1(C)Cc2cc(CC(N)=O)c(Cl)c(Cl)c2C1=O

HCID54379050

未命名化合物

PRODUCTS

生成物

结构：CCCC1(CC)Cc2cc(CC(N)=O)c(Cl)c(Cl)c2C1O

HCID54083871

未命名化合物

HCID54192808

未命名化合物

HCID54237806

未命名化合物

PROCEDURE

实验过程

When 6,7-dichloro-2-(i-propyl)-2-methyl-1-oxoindan-5-ylacetamide, 6,7-dichloro-2-ethyl-2-methyl-1-oxoindan-5-ylacetamide, and 6,7-dichloro-2-ethyl-2-(i-propyl)-1-oxoindan-5-ylacetamide are treated as described in Example 5, there are obtained 6,7-dichloro-2-(i-propyl)-2-methyl-1-hydroxyindan-5-ylacetamide, 6,7-dichloro-2-ethyl-2-methyl-1-hydroxyindan-5-ylacetamide and 6,7-dichloro-2-ethyl-2-(n-propyl)-1-hydroxyindan-5-ylacetamide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cd6596c45f304f02839676ce81683ea4
来源数据集: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04342776
来源说明: uspto-grants-1982_08

反应 SMILES

[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][C:7]([CH:14]([CH3:16])[CH3:15])([CH3:13])[C:8]2=[O:12])=[CH:4][C:3]=1[CH2:17][C:18]([NH2:20])=[O:19].[Cl:21][C:22]1[C:30]([Cl:31])=[C:29]2[C:25]([CH2:26][C:27]([CH2:34][CH3:35])([CH3:33])[C:28]2=[O:32])=[CH:24][C:23]=1[CH2:36][C:37]([NH2:39])=[O:38].[Cl:40][C:41]1[C:49]([Cl:50])=[C:48]2[C:44]([CH2:45][C:46]([CH2:55][CH3:56])(C(C)C)[C:47]2=[O:51])=[CH:43][C:42]=1[CH2:57][C:58]([NH2:60])=[O:59]>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH2:6][C:7]([CH:14]([CH3:16])[CH3:15])([CH3:13])[CH:8]2[OH:12])=[CH:4][C:3]=1[CH2:17][C:18]([NH2:20])=[O:19].[Cl:21][C:22]1[C:30]([Cl:31])=[C:29]2[C:25]([CH2:26][C:27]([CH2:34][CH3:35])([CH3:33])[CH:28]2[OH:32])=[CH:24][C:23]=1[CH2:36][C:37]([NH2:39])=[O:38].[Cl:40][C:41]1[C:49]([Cl:50])=[C:48]2[C:44]([CH2:45][C:46]([CH2:55][CH3:56])([CH2:3][CH2:2][CH3:10])[CH:47]2[OH:51])=[CH:43][C:42]=1[CH2:57][C:58]([NH2:60])=[O:59]