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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66689Generated: October 30, 2026

[6,7-Dichloro-1-hydroxy-2-methyl-2-(i-propyl)-indan-5-yl]oxyacetamide → 4-[6,7-Dichloro-1-hydroxy-2-methyl-2-(i-propyl)indan-5-yloxy]-3-hydroxy-3-pyrroline-2,5-dione

https://huagongshe.com/reaction/66689

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[6,7-Dichloro-1-hydroxy-2-methyl-2-(i-propyl)-indan-5-yl]oxyacetamideHCID 20530593—
ReactantHCID 86738520HCID 86738520—
Product4-[6,7-Dichloro-1-hydroxy-2-methyl-2-(i-propyl)indan-5-yloxy]-3-hydroxy-3-pyrroline-2,5-dioneHCID 54689956—

Reaction Steps

When [6,7-dichloro-1-hydroxy-2-methyl-2-(i-propyl)-indan-5-yl]oxyacetamide is utilized as starting material in the reaction with diethyl oxalate/potassium t-butoxide there is obtained 4-[6,7-dichloro-1-hydroxy-2-methyl-2-(i-propyl)indan-5-yloxy]-3-hydroxy-3-pyrroline-2,5-dione. Where [6,7-dichloro-2-ethyl-1-hydroxy-2-(n-propyl)indan-5-yl]oxyacetamide is utilized as starting material in this reaction there is obtained 4-[6,7-dichloro-2-ethyl-1-hydroxy-2-(n-propyl)indan-5-yloxy]-3-hydroxy-3-pyrroline-2,5-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04342776
Source datasetuspto-grants-1982_08
ORD IDord-957b94f1566a45a3a5cd7a2a20e0955c
Source noteuspto-grants-1982_08