HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,7-Dichloro-2-ethyl-2-(n-propyl)-1-hydroxyindan-5-ylacetamide → 4-(6,7-Dichloro-2-ethyl-2-methyl-1-hydroxyindan-5-yl)-3-hydroxy-3-pyrroline-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,7-Dichloro-2-ethyl-2-(n-propyl)-1-hydroxyindan-5-ylacetamide | HCID 54083871 | — |
| Reactant | 6,7-Dichloro-2-(i-propyl)-2-methyl-1-hydroxyindan-5-ylacetamide | HCID 54192808 | — |
| Reactant | 6,7-Dichloro-2-ethyl-2-methyl-1-hydroxyindan-5-ylacetamide | HCID 54237806 | — |
| Reactant | HCID 86738520 | HCID 86738520 | — |
| Product | 4-(6,7-Dichloro-2-ethyl-2-methyl-1-hydroxyindan-5-yl)-3-hydroxy-3-pyrroline-2,5-dione | HCID 54689955 | — |
| Product | 4-[6,7-Dichloro-2-(i-propyl)-2-methyl-1-hydroxyindan-5-yl]-3-hydroxy-3-pyrroline-2,5-dione | HCID 54689958 | — |
| Product | 4-[6,7-Dichloro-2-ethyl-2-(n-propyl)-1-hydroxyindan-5-yl]-3-hydroxy-3-pyrroline-2,5-dione | HCID 54689959 | — |
Reaction Steps
When 6,7-dichloro-2-(i-propyl)-2-methyl-1-hydroxyindan-5-ylacetamide, 6,7-dichloro-2-ethyl-2-methyl-1-hydroxyindan-5-ylacetamide, and 6,7-dichloro-2-ethyl-2-(n-propyl)-1-hydroxyindan-5-ylacetamide are utilized as starting materials in the diethyloxalate/potassium t-butoxide reaction there are obtained 4-[6,7-dichloro-2-(i-propyl)-2-methyl-1-hydroxyindan-5-yl]-3-hydroxy-3-pyrroline-2,5-dione, 4-(6,7-dichloro-2-ethyl-2-methyl-1-hydroxyindan-5-yl)-3-hydroxy-3-pyrroline-2,5-dione, and 4-[6,7-dichloro-2-ethyl-2-(n-propyl)-1-hydroxyindan-5-yl]-3-hydroxy-3-pyrroline-2,5-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04342776 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-cabe67cb34cb40489d9e816734a74467 |
| Source note | uspto-grants-1982_08 |