Pyridine → 1,1-Dimethylethyl 4-[5-(2-chloro-4-pyrimidinyl)-4-(3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-2-yl]-4-methyl-1-piperidinecarboxylate
Reaction equation
[F:35][c:36]1[c:37]([S:43](=[O:44])(=[O:45])[Cl:46])[c:38]([F:42])[cH:39][cH:40][cH:41]1.[NH2:1][c:2]1[c:3]([F:34])[c:4](-[c:8]2[n:9][c:10]([C:20]3([CH3:33])[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]3)[s:11][c:12]2-[c:13]2[n:14][c:15]([Cl:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1.[cH:47]1[cH:48][cH:49][n:50][cH:51][cH:52]1>>[NH:1]([c:2]1[c:3]([F:34])[c:4](-[c:8]2[n:9][c:10]([C:20]3([CH3:33])[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]3)[s:11][c:12]2-[c:13]2[n:14][c:15]([Cl:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1)[S:43]([c:37]1[c:36]([F:35])[cH:41][cH:40][cH:39][c:38]1[F:42])(=[O:44])=[O:45]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6f129a724655447eaf17929982eae8f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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