HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl acetoacetate → HCID 178429333, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,2,2-Trichloroethanimidamide | HCID 35608 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178429333 | HCID 178429333 | 46% |
Reaction Steps
A mixture of 44.4 g (0.28 mole) trichloroacetamidine, 32.0 g (0.28 mole) methylacetoacetate, 37.5 g (0.28 mole) potassium carbonate, and 450 ml water was stirred for 3 days. A trace of solid was removed by filtration and the filtrate was made acidic with hydrochloric acid. The product precipitated out to give 28.9 g (46% yield; mp 173°-174° C.). The structure was confirmed via mp*, infrared and elemental analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04343803 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-71fc33f291614c5e91f54f39326cf623 |
| Source note | uspto-grants-1982_08 |