5-Bromo-2-thiophenesulfonamide → 5-[5-(4-Chloro-phenyl)-7-(1-hydroxy-1-methyl-ethyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

HRID 667337Notes

Reaction equation

HRID 667337 reaction equation
[Br:23][c:24]1[cH:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[NH2:32])[s:28]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([CH3:15])([CH3:16])[OH:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[CH:22])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([CH3:15])([CH3:16])[OH:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[C:22][c:24]2[cH:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[NH2:32])[s:28]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 12413045-Bromo-2-thiophenesulfonamideHCID 86608078HCID 86608078, compound

Product 1

HCID 670009095-[5-(4-Chloro-phenyl)-7-(1-hydroxy-1-methyl-ethyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

Sources & evidence

ORD record
ord-7f717685e48541e5aaef2e4308cc794d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…