{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → {1-[4-(6-bromo-7-methoxy-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester
Reaction equation
[Br:37][c:38]1[cH:39][c:40]2[c:41](=[O:57])[c:42]([I:56])[c:43](-[c:50]3[cH:51][cH:52][cH:53][cH:54][cH:55]3)[o:44][c:45]2[cH:46][c:47]1[O:48][CH3:49].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](=[O:20])[c:21]4[c:22]([cH:23][cH:24][c:25]([F:26])[cH:27]4)[o:28][c:29]3-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:42]3[c:41](=[O:57])[c:40]4[cH:39][c:38]([Br:37])[c:47]([O:48][CH3:49])[cH:46][c:45]4[o:44][c:43]3-[c:50]3[cH:51][cH:52][cH:53][cH:54][cH:55]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-4c324da697e44c3bb71370e1ba5a5fa4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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