Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Alcohol → 2-Amino-3-morpholino-5-benzyloxypyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Alcohol | HCID 244 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 5-Bromo-3-morpholinopyrazin-2-amine | HCID 16740441 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 2-Amino-3-morpholino-5-benzyloxypyrazine | HCID 20528934 | — |
반응 단계
Sodium hydride (0.1 mole) is added to benzyl alcohol (0.1 mole) in 100 ml. dry benzene and the mixture is refluxed one to two hours. The cooled solution is treated with 0.1 mole of 2-amino-3-morpholino-5-bromopyrazine in 100 ml. of benzene and the resulting mixture refluxed for 20-60 hours whereupon it is cooled, washed with water, dried and evaporated to give 2-amino-3-morpholino-5-benzyloxypyrazine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04343802 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-211a8934f2b34af3a63246b2895799df |
| 출처 메모 | uspto-grants-1982_08 |