Ethanol → 4-[[4-(4-Pyridinyl)phenyl]methyl]-2-thiazolamine

HRID 667787Notes

Reaction equation

HRID 667787 reaction equation
[Br:10][c:11]1[cH:12][cH:13][c:14]([CH2:15][c:16]2[n:17][c:18]([NH2:21])[s:19][cH:20]2)[cH:22][cH:23]1.[Br:24][CH2:25][C:26](=[O:27])[CH2:28][c:29]1[cH:30][cH:31][c:32]([Br:33])[cH:34][cH:35]1.[CH2:40]([OH:41])[CH3:42].[NH2:36][C:37](=[S:38])[NH2:39].[n:1]1[cH:2][cH:3][c:4]([B:7]([OH:8])[OH:9])[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4](-[c:11]2[cH:12][cH:13][c:14]([CH2:15][c:16]3[n:17][c:18]([NH2:21])[s:19][cH:20]3)[cH:22][cH:23]2)[cH:5][cH:6]1

Participants

6

Reactant 5

HCID 702EthanolHCID 2723790ThioureaHCID 2734379(Pyridin-4-yl)boronic acidHCID 234041201-Bromo-3-(4-bromophenyl)propan-2-oneHCID 432604114-[(4-Bromophenyl)methyl]-1,3-thiazol-2-amine

Product 1

HCID 589307704-[[4-(4-Pyridinyl)phenyl]methyl]-2-thiazolamine

Sources & evidence

ORD record
ord-9f83ab18be1844c38ddd0b9d6b59ea73
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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