Ammonia → 8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepine

HRID 667789Notes

Reaction equation

HRID 667789 reaction equation
[C:1]([CH3:2])([N:4]1[CH:5]([CH2:23][NH:24][C:3](=[O:25])[CH3:26])[CH2:6][N:7]=[C:8]([c:16]2[c:17]([F:22])[cH:18][cH:19][cH:20][cH:21]2)[c:9]2[c:10]1[cH:11][cH:12][c:13]([Cl:15])[cH:14]2)=[O:27].[NH3:28]>>[C:1]1([CH3:2])=[N:24][CH2:23][CH:5]2[N:4]1[c:10]1[c:9]([cH:14][c:13]([Cl:15])[cH:12][cH:11]1)[C:8]([c:16]1[c:17]([F:22])[cH:18][cH:19][cH:20][cH:21]1)=[N:7][CH2:6]2

Participants

3

Reactant 2

HCID 222AmmoniaHCID 15563246N-[[1-Acetyl-7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methyl]acetamide

Product 1

HCID 110239098-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepine

Sources & evidence

ORD record
ord-c7507678d8964e88bf4ea8f44b3f42f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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