Methanol → 2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-pyridin-3-ol

HRID 667896Notes

Reaction equation

HRID 667896 reaction equation
[CH3:18][OH:19].[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH:7]=[C:8]([c:11]1[n:12][cH:13][cH:14][cH:15][c:16]1[OH:17])[CH2:9][CH2:10]2.[OH-:20].[OH-:22].[Pd+2:21]>>[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][CH:8]([c:11]1[n:12][cH:13][cH:14][cH:15][c:16]1[OH:17])[CH2:9][CH2:10]2

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 585625152-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)-pyridin-3-ol

Product 1

HCID 585628682-(1,4-Dioxa-spiro[4.5]dec-8-yl)-pyridin-3-ol

Sources & evidence

ORD record
ord-bb862d8d88dc45059475e1aa22b5621d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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