反应详情

A mixture of 10.0 g (0.05 mol) of 2,3,4,9-tetrahydro-N-methyl-1H-carbazol-2-amine and 70 ml of acetic anhydride was heated at reflux until complete solution occurred (2-3 min). After standing overnight at room temperature and further cooling at 0°, the precipitated solid was filtered, washed first with small portions of cold acetic anhydride and then thoroughly with anhydrous ether. The crude product was recrystallized from ethanol to give the title compound, mp 215°-216°.

1. temperaturewas heated
2. temperatureat reflux until complete solution
3. custom(2-3 min)
4. temperaturefurther cooling at 0°
5. filtrationthe precipitated solid was filtered
6. washwashed first with small portions of cold acetic anhydride
7. customThe crude product was recrystallized from ethanol