反应详情

A mixture of 0.1 mol of N-(1,3,4,9-tetrahydro-2H-carbazol-2-yl)acetamide, 0.15 mol of powdered KOH, and 75 ml of DMSO was stirred under nitrogen for 2 hr at room temperature. Methyl iodide (0.15 moL) was added in one portion, and, after brief cooling to moderate the exothermic reaction, the mixture was stirred at room temperature for 2 hr. The precipitate obtained by pouring the reaction mixture into excess water, was filtered, washed with water, and recrystallized from ethyl acetate to give the title compound, mp 171°-172°.

1. temperatureafter brief cooling
2. customthe exothermic reaction
3. stirringthe mixture was stirred at room temperature for 2 hr
4. customThe precipitate obtained
5. filtrationwas filtered
6. washwashed with water
7. customrecrystallized from ethyl acetate