Benzonitrile, 3-(bromomethyl)- → 4-{(3-Cyano-benzyl)-[4-(4-methoxycarbonyl-phenoxy)-phenyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[cH:16][cH:17][c:18]([O:21][c:22]3[cH:23][cH:24][c:25]([C:28](=[O:29])[O:30][CH3:31])[cH:26][cH:27]3)[cH:19][cH:20]2)[CH2:12][CH2:13]1.[C:32](#[N:33])[c:34]1[cH:35][c:36]([CH2:37][Br:38])[cH:39][cH:40][cH:41]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([c:15]2[cH:16][cH:17][c:18]([O:21][c:22]3[cH:23][cH:24][c:25]([C:28](=[O:29])[O:30][CH3:31])[cH:26][cH:27]3)[cH:19][cH:20]2)[CH2:37][c:36]2[cH:35][c:34]([C:32]#[N:33])[cH:41][cH:40][cH:39]2)[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-16f0989b68d44fe4af7d521320c2062f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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