Methanol → 7-Bromo-5-methoxyindoline

HRID 667975Notes

Reaction equation

HRID 667975 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][c:11]2[cH:12][c:13]([O:18][CH3:19])[cH:14][c:15]([Br:17])[c:16]21)([CH3:5])([CH3:6])[CH3:7].[CH3:23][OH:24].[Na+:22].[OH-:21].[OH2:20]>>[NH:8]1[CH2:9][CH2:10][c:11]2[cH:12][c:13]([O:18][CH3:19])[cH:14][c:15]([Br:17])[c:16]21

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 186292191h-Indole-1-carboxylic acid,7-bromo-2,3-dihydro-5-methoxy-,1,1-dimethylethyl ester

Product 1

HCID 184528187-Bromo-5-methoxyindoline

Sources & evidence

ORD record
ord-f3f705222240414e85cf4cf3a3a3acc1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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