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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66800Generated: October 30, 2026

Itaconic acid → trans-N-Decyl-2-[4-(4-carboxy-2-oxo-pyrrolidino)-phenyl]cyclopropanecarboxamide

https://huagongshe.com/reaction/66800

Reaction equation

Participants

RoleNameHCIDCharge
ReactantItaconic acidHCID 811—
Reactanttrans-N-Decyl-2-(4-aminophenyl)cyclopropanecarboxamideHCID 54265967—
Producttrans-N-Decyl-2-[4-(4-carboxy-2-oxo-pyrrolidino)-phenyl]cyclopropanecarboxamideHCID 54560922—

Reaction Steps

The title compound was prepared from trans-N-decyl-2-(4-aminophenyl)cyclopropanecarboxamide and itaconic acid, substantially according to the procedure of Example 10. It was recrystallized twice from ethanol to give a 47% yield of material having a melting point of 214°-215° C. The infrared spectrum (KBr disc) showed absorptions at 3280, 3125, 1680 and 1625 cm-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04343813
Source datasetuspto-grants-1982_08
ORD IDord-c73b4b93cc634a2c974110eb493f693e
Source noteuspto-grants-1982_08