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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 668168Generated: October 30, 2026

Toluene → 2-Chloro-5-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyrimidine

https://huagongshe.com/reaction/668168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTriethylamineHCID 8471—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Reactant4-Ethynyl-2-methylthiazoleHCID 11622334—
ReactantHCID 178420554HCID 178420554—
Product2-Chloro-5-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyrimidineHCID 57823029—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-51ae2f612c4e4bb0be32a482d52bfba3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)