5,5-Dimethylpiperidin-2-one → 5,5-Dimethyl-1-(5-phenylethynyl-pyridin-2-ylmethyl)-piperidin-2-one
Reaction equation
[CH3:17][C:18]1([CH3:25])[CH2:19][CH2:20][C:21](=[O:24])[NH:22][CH2:23]1.[c:1]1([C:7]#[C:8][c:9]2[cH:10][cH:11][c:12]([CH2:15][OH:16])[n:13][cH:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]#[C:8][c:9]2[cH:10][cH:11][c:12]([CH2:15][N:22]3[C:21](=[O:24])[CH2:20][CH2:19][C:18]([CH3:17])([CH3:25])[CH2:23]3)[n:13][cH:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-98e9447544024cabaab8e9fec421af60
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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