1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(3-isopropylisoxazol-5-yl)urea → 1-(3-Cyclopropylisoxazol-5-yl)-3-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:7][c:8]1[O:9][CH3:10])[n:11][cH:12][n:13][c:14]2[O:15][c:16]1[cH:17][c:18]([NH2:22])[cH:19][cH:20][cH:21]1.[CH3:41][O:42][c:43]1[cH:44][c:45]2[c:46]([O:55][c:56]3[cH:57][c:58]([NH:62][C:63](=[O:64])[NH:65][c:66]4[cH:67][c:68]([CH:71]([CH3:72])[CH3:73])[n:69][o:70]4)[cH:59][cH:60][cH:61]3)[n:47][cH:48][n:49][c:50]2[cH:51][c:52]1[O:53][CH3:54].[CH:23]1([c:24]2[cH:25][c:26]([NH:27][C:28](=[O:29])[O:30][c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[o:37][n:38]2)[CH2:39][CH2:40]1>>[CH3:41][O:42][c:43]1[cH:44][c:45]2[c:46]([O:55][c:56]3[cH:57][c:58]([NH:62][C:63](=[O:64])[NH:65][c:66]4[cH:67][c:68]([CH:71]5[CH2:72][CH2:73]5)[n:69][o:70]4)[cH:59][cH:60][cH:61]3)[n:47][cH:48][n:49][c:50]2[cH:51][c:52]1[O:53][CH3:54]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a69bd49c69de4eccb12bcb3fd188512e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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