Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54029577, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([OH:17])[CH:15]=2)[NH:10][C:9]=1[CH3:18].[CH2:19]([O:21][C:22](=[O:27])[C:23](Br)([CH3:25])[CH3:24])[CH3:20]>>[CH2:19]([O:21][C:22](=[O:27])[C:23]([O:17][C:14]1[CH:15]=[C:16]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9]([CH3:18])=[C:8]2[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])([CH3:25])[CH3:24])[CH3:20]Participants
3
Procedure
The above compound was prepared from 3-(2-chlorophenyl)-2-methyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester analogously to Example 10.
Sources & evidence
- ORD record
- ord-7ea6ac9f376f4257a6874beab79bd2f4
- Source dataset
- uspto-grants-1982_08
- Patent number
- US04343811
Reaction notes
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