Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 53741278, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([OH:17])[CH:15]=2)[N:10]([CH2:18][CH2:19][CH3:20])[C:9]=1[CH3:21].[CH2:22]([O:24][C:25](=[O:30])[C:26](Br)([CH3:28])[CH3:27])[CH3:23]>>[CH2:22]([O:24][C:25](=[O:30])[C:26]([O:17][C:14]1[CH:15]=[C:16]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH2:18][CH2:19][CH3:20])[C:9]([CH3:21])=[C:8]2[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])([CH3:28])[CH3:27])[CH3:23]Participants
3
Procedure
Following a procedure analogous to that of Example 10, the above compound was prepared from 3-(2-chloro-phenyl)-2-methyl-1-propyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester.
Sources & evidence
- ORD record
- ord-1a876f5ec9054c16be1baeb4602b6321
- Source dataset
- uspto-grants-1982_08
- Patent number
- US04343811
Reaction notes
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