Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-[1-Ethyl-3-(2-bromo-phenyl)-2-methyl-1H-indole-5-yloxy]-2-methyl-propanoic acid ethylester

HRID 66839Notes

Reaction equation

HRID 66839 reaction equation
[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][C:8]([OH:12])=[CH:9][CH:10]=2)[C:5]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[Br:19])=[C:4]1[CH3:20])[CH3:2].[CH2:21]([O:23][C:24](=[O:29])[C:25](Br)([CH3:27])[CH3:26])[CH3:22]>>[CH2:21]([O:23][C:24](=[O:29])[C:25]([O:12][C:8]1[CH:7]=[C:6]2[C:11](=[CH:10][CH:9]=1)[N:3]([CH2:1][CH3:2])[C:4]([CH3:20])=[C:5]2[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Br:19])([CH3:27])[CH3:26])[CH3:22]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529123HCID 20529123, compound

Product 1

HCID 545328232-[1-Ethyl-3-(2-bromo-phenyl)-2-methyl-1H-indole-5-yloxy]-2-methyl-propanoic acid ethylester

Procedure

The above compound was prepared from 1-ethyl-3-(2-bromo-phenyl)-2-methyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester analogously to Example 10.

Sources & evidence

ORD record
ord-2487235408fd47b8bfa16f4899d5ff4b
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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