Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54313083, compound

HRID 66841Notes

Reaction equation

HRID 66841 reaction equation
[CH2:1]([N:5]1[C:13]2[C:8](=[CH:9][C:10]([OH:14])=[CH:11][CH:12]=2)[C:7]([C:15]2[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=2)=[C:6]1[CH3:22])[CH2:2][CH2:3][CH3:4].[CH2:23]([O:25][C:26](=[O:31])[C:27](Br)([CH3:29])[CH3:28])[CH3:24]>>[CH2:23]([O:25][C:26](=[O:31])[C:27]([O:14][C:10]1[CH:9]=[C:8]2[C:13](=[CH:12][CH:11]=1)[N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6]([CH3:22])=[C:7]2[C:15]1[CH:16]=[CH:17][C:18]([F:21])=[CH:19][CH:20]=1)([CH3:29])[CH3:28])[CH3:24]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529079HCID 20529079, compound

Product 1

HCID 54313083HCID 54313083, compound

Procedure

The above compound was prepared from 1-butyl-3-(4-fluoro-phenyl)-2-methyl-1H-indole-5-ol and 2-bromo-2-methylpropanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-c603018fa65648ef99824a1b757117ca
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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