Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 53812607, compound

HRID 66843Notes

Reaction equation

HRID 66843 reaction equation
[F:1][C:2]([F:22])([F:21])[C:3]1[CH:4]=[C:5]([C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([OH:18])[CH:16]=3)[N:11]([CH3:19])[C:10]=2[CH3:20])[CH:6]=[CH:7][CH:8]=1.[CH2:23]([O:25][C:26](=[O:31])[C:27](Br)([CH3:29])[CH3:28])[CH3:24]>>[CH2:23]([O:25][C:26](=[O:31])[C:27]([O:18][C:15]1[CH:16]=[C:17]2[C:12](=[CH:13][CH:14]=1)[N:11]([CH3:19])[C:10]([CH3:20])=[C:9]2[C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:1])([F:21])[F:22])[CH:4]=1)([CH3:29])[CH3:28])[CH3:24]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 205290833-(3-trifluoromethyl-phenyl)-1,2-dimethyl-1H-indole-5-ol

Product 1

HCID 53812607HCID 53812607, compound

Procedure

The above compound was prepared from 3-(3-trifluoromethyl-phenyl)-1,2-dimethyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-2bc5030e111f4d9fbc4a97e25097bc54
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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