Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54323078, compound
Reaction equation
[CH3:1][C:2]1[N:3]([CH2:19][CH2:20][CH3:21])[C:4]2[C:9]([C:10]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH3:17])=[CH:8][C:7]([OH:18])=[CH:6][CH:5]=2.[CH2:22]([O:24][C:25](=[O:30])[C:26](Br)([CH3:28])[CH3:27])[CH3:23]>>[CH2:22]([O:24][C:25](=[O:30])[C:26]([CH3:28])([O:18][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]([CH2:19][CH2:20][CH3:21])[C:2]([CH3:1])=[C:10]2[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH3:17])[CH3:27])[CH3:23]Participants
3
Procedure
The above compound was prepared from 2-methyl-3-(2-methyl-phenyl)-1-propyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.
Sources & evidence
- ORD record
- ord-62684b2f1ca446ec87aefe18813c3f94
- Source dataset
- uspto-grants-1982_08
- Patent number
- US04343811
Reaction notes
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