2,4-Dichloro-5-(trifluoromethyl)pyrimidine → Diethyl (4-{[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]amino}-3-ethoxybenzyl)phosphonate
Reaction equation
[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH2:9][c:10]1[cH:11][cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[c:21]([Cl:23])[n:22]2)[cH:14][cH:15]1.[CH2:28]([CH3:29])[O:30][P:31]([CH2:32][c:33]1[cH:34][cH:35][c:36]([NH2:37])[c:38]([O:39][CH2:40][CH3:41])[cH:42]1)(=[O:43])[O:44][CH2:45][CH3:46].[Cl:47][c:48]1[n:49][c:50]([Cl:51])[c:52]([C:53]([F:54])([F:55])[F:56])[cH:57][n:58]1>>[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH2:9][c:10]1[cH:11][cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[c:21]([Cl:23])[n:22]2)[c:14]([O:30][CH2:28][CH3:29])[cH:15]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-f6264e8dd3ca48f9bdb4f2f1de7fcd5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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