Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54359310, compound

HRID 66850Notes

Reaction equation

HRID 66850 reaction equation
[CH3:1][C:2]1[N:3]([CH2:20][CH2:21][CH3:22])[C:4]2[C:9]([C:10]=1[CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[CH:8][C:7]([OH:19])=[CH:6][CH:5]=2.[CH2:23]([O:25][C:26](=[O:31])[C:27](Br)([CH3:29])[CH3:28])[CH3:24]>>[CH2:23]([O:25][C:26](=[O:31])[C:27]([CH3:29])([O:19][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]([CH2:20][CH2:21][CH3:22])[C:2]([CH3:1])=[C:10]2[CH2:11][CH2:12][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1)[CH3:28])[CH3:24]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529105HCID 20529105, compound

Product 1

HCID 54359310HCID 54359310, compound

Procedure

The above compound was prepared from 2-methyl-3-(2-phenyl-ethyl)-1-propyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-10fe4b4f46404831a61f9d8cbb7bf5a5
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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