Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54296867, compound

HRID 66858Notes

Reaction equation

HRID 66858 reaction equation
[CH:1]([C:4]1[N:5]([CH3:20])[C:6]2[C:11]([C:12]=1[C:13]1[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=1)=[CH:10][C:9]([OH:19])=[CH:8][CH:7]=2)([CH3:3])[CH3:2].[CH2:21]([O:23][C:24](=[O:29])[C:25](Br)([CH3:27])[CH3:26])[CH3:22]>>[CH2:21]([O:23][C:24](=[O:29])[C:25]([O:19][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[N:5]([CH3:20])[C:4]([CH:1]([CH3:3])[CH3:2])=[C:12]2[C:13]1[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=1)([CH3:27])[CH3:26])[CH3:22]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529084HCID 20529084, compound

Product 1

HCID 54296867HCID 54296867, compound

Procedure

The above compound was prepared from 2-isopropyl-1-methyl-3-(4-pyridyl)-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-dbc81594f74442b59666a9d7721e4032
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

Loading…