Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 53680788, compound

HRID 66859Notes

Reaction equation

HRID 66859 reaction equation
[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][C:8]([OH:12])=[CH:9][CH:10]=2)[C:5]([C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)=[C:4]1[CH3:19])[CH3:2].[CH2:20]([O:22][C:23](=[O:28])[C:24](Br)([CH3:26])[CH3:25])[CH3:21]>>[CH2:20]([O:22][C:23](=[O:28])[C:24]([O:12][C:8]1[CH:7]=[C:6]2[C:11](=[CH:10][CH:9]=1)[N:3]([CH2:1][CH3:2])[C:4]([CH3:19])=[C:5]2[C:13]1[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=1)([CH3:26])[CH3:25])[CH3:21]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529075HCID 20529075, compound

Product 1

HCID 53680788HCID 53680788, compound

Procedure

The above compound was prepared from 1-ethyl-2-methyl-3-(4-pyridyl)-1H-indole-5-ol and 2-bromo-2-methylpropanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-3c60f2fe7e4a43629becc7612e46721b
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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