Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 20529070, compound

HRID 66860Notes

Reaction equation

HRID 66860 reaction equation
[CH3:1][C:2]1[N:3]([CH2:18][CH2:19][CH3:20])[C:4]2[C:9]([C:10]=1[C:11]1[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=1)=[CH:8][C:7]([OH:17])=[CH:6][CH:5]=2.[CH2:21]([O:23][C:24](=[O:29])[C:25](Br)([CH3:27])[CH3:26])[CH3:22]>>[CH2:21]([O:23][C:24](=[O:29])[C:25]([CH3:27])([O:17][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]([CH2:18][CH2:19][CH3:20])[C:2]([CH3:1])=[C:10]2[C:11]1[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=1)[CH3:26])[CH3:22]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 205291902-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-ol

Product 1

HCID 20529070HCID 20529070, compound

Procedure

The above compound was prepared from 2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-ol and 2-bromo-2-methylpropanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-0ab4f123a93d4c4a8580c96b5efc01f5
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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