Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54340005, compound

HRID 66861Notes

Reaction equation

HRID 66861 reaction equation
[CH:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([OH:13])=[CH:10][CH:11]=2)[C:6]([C:14]2[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=2)=[C:5]1[CH3:20])([CH3:3])[CH3:2].[CH2:21]([O:23][C:24](=[O:29])[C:25](Br)([CH3:27])[CH3:26])[CH3:22]>>[CH2:21]([O:23][C:24](=[O:29])[C:25]([O:13][C:9]1[CH:8]=[C:7]2[C:12](=[CH:11][CH:10]=1)[N:4]([CH:1]([CH3:3])[CH3:2])[C:5]([CH3:20])=[C:6]2[C:14]1[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=1)([CH3:27])[CH3:26])[CH3:22]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529203HCID 20529203, compound

Product 1

HCID 54340005HCID 54340005, compound

Procedure

The above compound was prepared from 1-isopropyl-2-methyl-3-(4-pyridyl)-1H-indole-5-ol and 2-bromo-2-methylpropanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-6b005a781c914c919778ba330eb2319c
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

Loading…