Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 53993162, compound

HRID 66863Notes

Reaction equation

HRID 66863 reaction equation
[CH2:1]([N:5]1[C:13]2[C:8](=[CH:9][C:10]([OH:14])=[CH:11][CH:12]=2)[C:7]([C:15]2[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=2)=[C:6]1[CH3:21])[CH2:2][CH2:3][CH3:4].[CH2:22]([O:24][C:25](=[O:30])[C:26](Br)([CH3:28])[CH3:27])[CH3:23]>>[CH2:22]([O:24][C:25](=[O:30])[C:26]([O:14][C:10]1[CH:9]=[C:8]2[C:13](=[CH:12][CH:11]=1)[N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6]([CH3:21])=[C:7]2[C:15]1[CH:16]=[CH:17][N:18]=[CH:19][CH:20]=1)([CH3:28])[CH3:27])[CH3:23]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529074HCID 20529074, compound

Product 1

HCID 53993162HCID 53993162, compound

Procedure

In accordance with a procedure analogous to that of Example 10, the above compound was prepared from 1-butyl-2-methyl-3-(4-pyridyl)-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester.

Sources & evidence

ORD record
ord-52bcd48168eb4e75a5e49ddf90a03c5c
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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