Acetate → Ethyl 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylate

HRID 668683Notes

Reaction equation

HRID 668683 reaction equation
[CH3:1][N:2]([N:3]=[O:4])[C:5]([NH:6][N+:7]([O-:8])=[O:9])=[NH:10].[CH3:41][C:42](=[O:43])[OH:44].[F:16][c:17]1[cH:18][c:19]([CH:25]=[CH:26][C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:20][cH:21][c:22]1[O:23][CH3:24].[K+:12].[N+:13](=[N-:14])=[CH2:15].[O-:33][C:34]([CH3:35])=[O:36].[O-:37][C:38]([CH3:39])=[O:40].[OH-:11].[Pd+2:32]>>[CH2:15]1[CH:25]([c:19]2[cH:18][c:17]([F:16])[c:22]([O:23][CH3:24])[cH:21][cH:20]2)[CH:26]1[C:27](=[O:28])[O:29][CH2:30][CH3:31]

Participants

9

Reactant 8

HCID 175Acetate2×HCID 176Acetic AcidHCID 813Potassium CationHCID 961HydroxideHCID 9550DiazomethaneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 53705486HCID 53705486, compoundHCID 135436526N-Methyl-N'-nitro-N-nitrosoguanidine

Product 1

HCID 58566289Ethyl 2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylate

Sources & evidence

ORD record
ord-ca082c760efe49679ad7be6164550726
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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