Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid ethylester

HRID 66869Notes

Reaction equation

HRID 66869 reaction equation
[CH3:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([OH:11])[CH:9]=2)[N:4]([CH2:12][CH2:13][CH3:14])[C:3]=1[C:15]1[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=1.[CH2:21]([O:23][C:24](=[O:29])[C:25](Br)([CH3:27])[CH3:26])[CH3:22]>>[CH2:21]([O:23][C:24](=[O:29])[C:25]([CH3:27])([O:11][C:8]1[CH:9]=[C:10]2[C:5](=[CH:6][CH:7]=1)[N:4]([CH2:12][CH2:13][CH3:14])[C:3]([C:15]1[CH:16]=[CH:17][N:18]=[CH:19][CH:20]=1)=[C:2]2[CH3:1])[CH3:26])[CH3:22]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529200HCID 20529200, compound

Product 1

HCID 538957452-methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid ethylester

Procedure

The above compound was prepared from 3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-b71a51805885474895e43a871cedf7fa
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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