Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-[11-(2-Quinolyl)-7,8,9,10-tetrahydro-6H-azepino[1,2-a]-indole-2-yloxy]-2-methyl-propanoic acid ethylester

HRID 66870Notes

Reaction equation

HRID 66870 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[C:17]([OH:20])[CH:18]=2)[N:13]2[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][C:12]=12.[CH2:26]([O:28][C:29](=[O:34])[C:30](Br)([CH3:32])[CH3:31])[CH3:27]>>[CH2:26]([O:28][C:29](=[O:34])[C:30]([O:20][C:17]1[CH:18]=[C:19]2[C:14](=[CH:15][CH:16]=1)[N:13]1[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][C:12]1=[C:11]2[C:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:1]=1)([CH3:32])[CH3:31])[CH3:27]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 2052918311-(2-quinolyl)-7,8,9,10-tetrahydro-6H-azepino[1,2-a]indole-2-ol

Product 1

HCID 539590802-[11-(2-Quinolyl)-7,8,9,10-tetrahydro-6H-azepino[1,2-a]-indole-2-yloxy]-2-methyl-propanoic acid ethylester

Procedure

This compound was prepared from 11-(2-quinolyl)-7,8,9,10-tetrahydro-6H-azepino[1,2-a]indole-2-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-ef900cfe2ada495d8e3909eeee52ac97
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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