Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 53908130, compound
Reaction equation
[CH3:1][C:2]1[N:3]([CH2:18][CH2:19][CH3:20])[C:4]2[C:9]([C:10]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[CH:8][CH:7]=[C:6]([OH:17])[CH:5]=2.[CH2:21]([O:23][C:24](=[O:29])[C:25](Br)([CH3:27])[CH3:26])[CH3:22]>>[CH2:21]([O:23][C:24](=[O:29])[C:25]([CH3:27])([O:17][C:6]1[CH:5]=[C:4]2[C:9]([C:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[C:2]([CH3:1])[N:3]2[CH2:18][CH2:19][CH3:20])=[CH:8][CH:7]=1)[CH3:26])[CH3:22]Participants
3
Procedure
The above compound was prepared from 2-methyl-3-phenyl-1-propyl-1H-indole-6-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10 (solvent: glycol dimethylether).
Sources & evidence
- ORD record
- ord-a67aae115334485988aaec991937344f
- Source dataset
- uspto-grants-1982_08
- Patent number
- US04343811
Reaction notes
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