Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-Methyl-2-[2-methyl-3-phenyl-1H-indole-4-yloxy]-propanoic acid ethylester

HRID 66880Notes

Reaction equation

HRID 66880 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[CH:5]=[CH:6][CH:7]=[C:8]([OH:17])[C:9]=2[C:10]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[CH2:18]([O:20][C:21](=[O:26])[C:22](Br)([CH3:24])[CH3:23])[CH3:19]>>[CH2:18]([O:20][C:21](=[O:26])[C:22]([CH3:24])([O:17][C:8]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:9]=1[C:10]([C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)=[C:2]([CH3:1])[NH:3]2)[CH3:23])[CH3:19]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 205291612-Methyl-3-phenyl-1H-indole-4-ol

Product 1

HCID 538412442-Methyl-2-[2-methyl-3-phenyl-1H-indole-4-yloxy]-propanoic acid ethylester

Procedure

The above compound was prepared from 2-methyl-3-phenyl-1H-indole-4-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-dea411165529488f819c4a39fa4736ef
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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