Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54350561, compound

HRID 66881Notes

Reaction equation

HRID 66881 reaction equation
[CH2:1]([C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([OH:17])[CH:15]=2)[N:10]([CH2:18][CH2:19][CH3:20])[C:9]=1[CH3:21])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:22]([O:24][C:25](=[O:30])[C:26](Br)([CH3:28])[CH3:27])[CH3:23]>>[CH2:22]([O:24][C:25](=[O:30])[C:26]([O:17][C:14]1[CH:15]=[C:16]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH2:18][CH2:19][CH3:20])[C:9]([CH3:21])=[C:8]2[CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)([CH3:28])[CH3:27])[CH3:23]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 205291433-benzyl-2-methyl-1-propyl-1H-indole-5-ol

Product 1

HCID 54350561HCID 54350561, compound

Procedure

The above compound was prepared from 3-benzyl-2-methyl-1-propyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-5ae043991ea84928ba5efc35c4fc5df6
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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