Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 54450168, compound

HRID 66882Notes

Reaction equation

HRID 66882 reaction equation
[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[C:13]([OH:16])[CH:14]=3)[N:9]([CH2:17][CH2:18][CH3:19])[C:8]=2[CH3:20])=[CH:4][CH:3]=1.[CH2:23]([O:25][C:26](=[O:31])[C:27](Br)([CH3:29])[CH3:28])[CH3:24]>>[CH2:23]([O:25][C:26](=[O:31])[C:27]([O:16][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][CH:12]=1)[N:9]([CH2:17][CH2:18][CH3:19])[C:8]([CH3:20])=[C:7]2[CH2:6][C:5]1[CH:21]=[CH:22][C:2]([Cl:1])=[CH:3][CH:4]=1)([CH3:29])[CH3:28])[CH3:24]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 205290773-[(4-Chlorophenyl)methyl]-2-methyl-1-propyl-1H-indol-5-ol

Product 1

HCID 54450168HCID 54450168, compound

Procedure

In accordance with a procedure analogous to that of Example 10, the above compound was prepared from 3-(4-chlorobenzyl)-2-methyl-1-propyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester.

Sources & evidence

ORD record
ord-3a81d6936d66406f9c790bca258e043c
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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